Europäische Wissenschaftliche Gesellschaft




Erfolgreich durch internationale Zusammenarbeit

AI in Healthcare

Cite as: Archiv EuroMedica. 2025. 15; 1. DOI 10.35630/2025/15/1.104

Received 15 January 2025;
Accepted 17 February 2025;
Published 23 February 2025

ARTIFICIAL INTELLIGENCE-POWERED INSIGHTS: EXPLORING THE IMPACT OF ARTERIAL HYPERTENSION ON INGUINAL HERNIOPLASTY CONSEQUENCES

Andrey Protasov 1 orcid id logo, Mekhaeel Mekhaeel1 orcid id logo,
Sameh Salem1email orcid id logo, Watban Khalid Al-Tekreeti2 orcid id logo,
Eman Abdulqader Abduhalim Abdo3 orcid id logo, Abd Alhakem Alhatem4 orcid id logo

1Department of Operative Surgery and Clinical Anatomy named after I.D. Kirpatovsky. Medical institute. Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University), Moscow, Russia
2Department of Mechanical Engineering Technologies, Academy of Engineering. Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University), Moscow, Russia.
3Department of Oncology and Roentgenology named after V.P. Kharchenko. Medical Institute. Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University), Moscow, Russia
4Department of Surgery. Medical institute. Peoples’ Friendship University of Russia named after Patrice Lumumba (RUDN University). Moscow, Russia

download article (pdf)

  samehhadhoud2020@gmail.com

ABSTRACT

Aims: To analyze potential influences of primary arterial hypertension in patients with an inguinal hernia after Liechtenstein open inguinal hernia repair by using different types of surgical mesh implants.

Method: 40 patients with inguinal hernia were operated by the Lichtenstein repair using different types of mesh implants during the period between January 2022 and the end of December 2024. The patients were splitted into 2 equal groups (no=20); Group A (Normotensive Patients) and Group B (Hypertensive Patients),and the results were analyzed using machine learning Artificial Intelligence programming language; Python.

Results: Duration of herniation, total hospitalization stays, time of operation and the incidence of postoperative complications — the results of the t-tests show no statistically significant differences among both groups.

Conclusions: In our study, we found that hypertension status does not significantly impacts upon the outcomes of inguinal hernia repair.

Keywords: Artificial intelligence; Hernia; Hypertriton; Lichtenstein; Surgical mesh.

INTRODUCTION

The international guidelines for inguinal hernioplasty still consider the Liechtenstein technique as the reference standard [1] among more than 300 available repair methods [2] for inguinal hernia, which account for about 10-15% of the globally operated surgical procedures annually [3]. The pathogenesis of abdominal wall hernia and its recurrence is complex and multifactorial [4], being commoner among patients with connective tissue disorders and abdominal aortic aneurysms. This is evidenced by the thinning and disturbance of collagen fibres of rectus sheath in inguinal hernia patients in comparison to normal population. Even more, direct inguinal hernias possess thinner diameter of collagen fibres in the rectus sheath and a higher amount of interfibrillar matrix of fascia transversalis, in comparison to oblique hernias. Subserosal fibrosis are present in both types and may be attributed to the hernia itself, rather than the cause [5].

Patients with varicocele have a potential high risk of developing chronic venous disease and inguinal hernias over time, demonstrating a strong pathogenic link among three conditions, where an imbalance of the extracellular matrix (ECM), in the form of elevated levels of matrix metalloproteinases (MMP), particularly MMP-9, is found in these three conditions [6]. Furthermore, MMP-2 levels are elevated in patients with direct inguinal hernia, MMP-1 is associated with incisional and recurrent inguinal hernias which are also associated with elevated levels MMP-13 expression [7].

Other evidence of the ultimate relation between the coexistence of vascular disease and inguinal hernia is that vascular system consists of specialized cells surrounded by a dynamic ECM that not only provides structure through connections of cells within the network, but also instructs cellular function by facilitating the absorption of growth factors by the cells of the vascular system, which becomes dysregulated upon disease [8].The relation between abdominal aortic aneurysm (AAA) and abdominal hernias do exists, but doesn’t involve the size or even the rupture of the AAA, denning the relation between hernia and the aggressiveness of the AAA [9]. Even more, the prevalence of inguinal hernia is higher among patients with thoracic aortic diseases [10]. This fact makes us consider screening of aortic aneurysm in geriatric patients with inguinal hernia [11].

Using Artificial intelligence programs in hernia surgery e.g., Python [12] improved computer-vision methodology from supervised learning and machine learning algorithms in detecting wounds after inguinal hernia surgery, recognition of vas deferens during laparoscopic inguinal hernia surgery more accurately as well as the development of a laparoscopic training system for offering online training to surgeons [13]. Beside the development of an automated phase-recognition system for identifying surgical phases in Transabdominal Preperitoneal (TAPP) procedures, and a computerized vision algorithm designed to recognize surgical steps in videos of totally extraperitoneal (TEP) inguinal hernia repair automatically [14]. In addition, Applying Artificial intelligence in abdominal hernia surgery had led to sustainable healthcare for abdominal hernia patients as it enhances the development of computer analytics improving patient outcomes [15].

METHODS

Our study was carried on 40 patients diagnosed with inguinal hernias and operated by the Liechtenstein using different types of surgical mesh implants in the clinical hospital no. 85 FMBA, Moscow, Russia.

Inclusion criteria:

  1. Patients with unilateral, primary, uncomplicated inguinal hernia.
  2. Patients between 20-71 years.
  3. Patients operated using Liechtenstein technique.

Exclusion criteria:

  1. Patients with bilateral, recurrent, complicated inguinal hernia.
  2. Patients younger than 20 years and older than71 years.
  3. Patients operated laparoscopically or by open surgery by other techniques other than Lichtenstein.

Our study group was splited into 2 equally divided subgroup;

In Group A- patients (No=20) normotensive patients. Average age was 51.45 years. This groups contains 20 male patients; 16 patients with right inguinal hernia and 4 with left inguinal hernia. The ratio of oblique to direct inguinal hernia 12:8. In this group we used 8 PolypropyleneTM, 6 PartieneTM, 5 ProgripTM and 1 Bard 3D MaxTM mesh implants (Table 1).

While in Group B- patients (N0=20) hypertensive patients. Average age was 55.95 years. This groups contains 18 male patients and 2 female patients; 10 patients with right inguinal hernia and 10 with left inguinal hernia. The ratio of oblique to direct inguinal hernia 10:10. In this group we used 14 PolypropyleneTM and 6 PartieneTM (Table 2).

Table 1. The demographics of group A (Normotensive Patients)

Metric Mean Standard Error Median Mode Standard deviation Range Minimum Maximum
Age (years) 51.45 3.03 53 70 13.56 43 27 70
Duration of Herniation (months) 24.75 8.58 7.5 6 38.39 117 3 120
Hernia Length (cm) 6.9 0.61 6 6 2.71 9 3 12
Hernia Width (cm) 4.68 0.28 4.5 4 1.26 4.5 2.5 7
Hernia Height (cm) 3.75 0.45 3.5 3 1.28 4 2 6
Hernia Volume (cm³) 85.35 21.11 39 12 94.41 276 12 288
External Inguinal Ring Size (cm) 2.5 0.11 2.5 2.5 0.51 2 1.5 3.5

Table 2. The demographics of group B (Hypertensive Patients)

Metric Mean Standard Error Median Mode Standard deviation Range Minimum Maximum
Age (years) 55.95 2.96 63 64 13.26 41 27 68
Duration of Hernia (month) 22.7 4.41 18 24 19.70 58 2 60
Hernia Length (cm) 7.35 0.88 6 5 3.95 13 2 15
Hernia Width (cm) 4.7 0.33 4.5 4 1.49 5 2 7
Hernia Height (cm) 3.29 0.61 3 2 1.60 4 2 6
Hernia Volume (cm³) 86.3 28.05 31 25 125.46 498 6 504
External Inguinal Ring Size (cm) 2.35 0.19 2.5 1.5 0.83 2.5 1.5 4

The statistical data was analyzed by using machine learning Artificial Intelligence programming language; Python. The analysis included the following data:

  1. Patients’ demographics:
    1. Sex.
    2. Age.
    3. Duration of herniation.
    4. Hernia size.
    5. External inguinal ring size.
    6. Hernia site (Right: Left).
    7. Hernia type (Oblique: Direct).
    8. Associated comorbidities other than hypertension (Only in second group) and the percentage of each.
  2. Operative data:
    1. Type of anathesia.
    2. Size of hernial sac.
    3. Mesh type.
    4. Mesh size.
    5. Operative-time.
  3. Post-operative data:
    1. Total hospitalization duration (beds/day).
    2. Post-operative complications.
    3. Complications during short-term follow-up for 6 months.

Right-sided hernias are more common in Group A (61.54%), while left-sided hernias are predominant in Group B (71.43%). Direct hernias show a slightly higher prevalence in Group B (55.56%), whereas oblique hernias are more frequent in Group A (54.55%) [Table 3].

Table 3. The distribution of hernia site (Right: left) and hernia types (Direct: Oblique) among both study groups

Metric Group A (Normotensive) Group B (Hypertensive) Grand Total Group A (%) Group B (%)
Sum of Hernia Site (Right) 16 10 26 61.54% 38.46%
Sum of Hernia Site (Left) 4 10 14 28.57% 71.43%
Sum of Hernia Type (Direct) 8 10 18 44.44% 55.56%
Sum of Hernia Type (Oblique) 12 10 22 54.55% 45.45%

The average age was higher in Group B versus Group A (55.95 vs. 51.45 years) (Figure 1), with a slightly shorter herniation duration (22.7 vs. 24.75 months) (Figure 2).

Figure 1. Average age in both groups

Figure 1. Average age in both groups

Figure 2. Average duration of herniation in both groups

Figure 2. Average duration of herniation in both groups

Preoperative abdominal ultrasonographic examination was done for detecting the size of the external inguinal ring and the dimensions of the hernial sacs in both groups (Table 4).

Table 4. Average dimensions of the external inguinal ring and hernial sacs

Metric Group A (Normotensive) Group B (Hypertensive) Grand Total
Average External Inguinal Ring Size (cm) 2.5 2.35 2.43
Average Length of Hernial Sac (cm) 6.75 7.6 7.18
Average Width of Hernial Sac (cm) 3.9 4.63 4.26
Average Height of Hernial Sac (cm) 3.0 3.19 3.10
Average Volume of Hernial Sac (cm³) 99.93 135.1 117.51

In group B (hypertensive patients), we found 13 (65%) patients with associated comorbidities other than arterial hypertension (8 (40%) patients with cardiovascular diseases, 3(15%) with gastrointestinal diseases and 2(10%) patients with metabolic diseases) [Table 5].

Table 5. Associated comorbidities in group B patients

Associated disease Incidence
Congestive heart failure 5/20 (25%)
Coronary heart disease 2/20 (10%)
Chronic gastritis 2/20 (10%)
Chronic cholecystitis 1/20 (5%)
Varicocele 1/20 (5%)
Type II diabetes mellitus 1/20 (5%)
Dyslipidemia 1/20 (5%)
Grand total 13/20 (65%)

RESULTS

Operative results

Type of anesthesia

Spinal anesthesia is the most used technique in both groups, slightly higher in Group B (52.63%). Endotracheal anesthesia is uniquely applied in Group A patients (100%) (Table 6).

Table 6. Types of used anathesia in both groups

Anesthestic route Group A (Normotensive) Group B (Hypertensive) Grand Total Group A (%) Group B (%)
Spinal 18 20 38 47.37% 52.63%
Endotracheal 2 0 2 100.00% 0.00%

Types of used mesh implants

For group A- we used 8 PolypropyleneTM, 6 PartieneTM, 5 ProgripTM and 1 Bard 3D MaxTM mesh implants, while in group B- patients (N0=20) hypertensive patients. Average age was 55.95 years. This groups included 18 man and 2 women; 10 patients with right inguinal hernia and 10 with left inguinal hernia. The ratio of oblique to direct inguinal hernia 10:10. In this group we used 14 PolypropyleneTM and 6 PartieneTM (Table 7). Mesh dimensions are mentioned (Table 8).

Table 7. Types and distribution of surgical mesh implants in both groups

Mesh type Group A (Normotensive) Group B (Hypertensive) Grand Total Group A (%) Group B (%)
PolypropyleneTM 8 14 22 36.36% 63.64%
ParieteneTM 6 6 12 50.00% 50.00%
ProgripTM 5 0 5 100.00% 0.00%
Bard 3D MaxTM 1 0 1 100.00% 0.00%

Table 8. Average dimensions of the used mesh implants in both groups


Average Mesh Length (cm) Average Mesh Width (cm) Average Mesh Area (cm²)
Group A (Normotensive) 8.95 10.8 96.3
Group B (Hypertensive) 7.35 11.6 89.85
Grand Total 8.15 11.2 93.08

Polypropylene mesh is more commonly used in Group B (63.64%), while Progrip and Bard 3D Max meshes are exclusively used in Group A.

The average operative time was in group A (normotensive patients), only 5 minutes less than that of group B (hypertensive patients) (Table 9) (Figure 3).

Table 9 Average operative time (in minutes) for both groups

Group A (Normotensive) Group B (Hypertensive) Grand Total
44.5 50.25 47.375

Figure 3. Average operative time in both groups

Figure 3. Average operative time in both groups

The average duration of hospitalization shows no significant differences among both groups; 4.9 days for group A (normotensive patients) versus 4.95 days for group B (hypertensive patients) (Table 10) (Figure 4).

Table 10. Average duration of total hospitalization (beds/day)

Group A (Normotensive) Group B (Hypertensive) Grand Total
4.9 4.95 4.925

Figure 4. Average duration of total hospitalization (beds/day).

Figure 4. Average duration of total hospitalization (beds/day).

Post-operative complications

The incidence of complications during the post-operative period included;

In group A; 2 patients had post-operative pain which was relieved by using NSAIDs.

For group B; 4 patients had post-operative pain which was relieved by using NSAIDs and 1 patient had foreign body sensation (Table 11).

Table 11. Post-operative complications in both groups.


Group A Group B
Post-operative pain 2/20 (10%) 4/20 (20%)
Foreign body sensation 0/20 (0%) 1/20 (5%)

During the short-term follow up

In group A- No complications.

In group B- No complications.

Not a single case of hernia recurrence had been recorded among both groups.

DISCUSSION

In an attempt to understand the possible effects of arterial hypertension upon the consequences of open anterior inguinal hernia repair, we correlated the following parameters; Duration of hernaition, hernia Characteristics site, mesh dimensions, operative-time and hospitalization stays (Table 12).

Table 12: Comparison of Hernia Characteristics, Surgical Parameters, and Hospitalization Data by Hernia Site (Right/Left)

Metric Group A (Left) Group A (Right) Group B (Left) Group B (Right) Grand Total (Left) Grand Total (Right)
Average of Total Hospitalization (beds/day) 4.25 5.06 5.1 4.8 4.86 4.93
Average of Duration of Herniation (Months) 28.25 23.88 17.4 28.0 20.5 25.46
Average of Hernia Length (cm) 6.5 7.0 7.1 7.6 6.93 7.23
Average of Hernia Width (cm) 4.25 4.78 4.5 4.9 4.43 4.83
Average of Hernia Height (cm) 3.67 3.8 2.33 4.0 3.0 3.89
Average of Hernia Volume (cm³) 97.25 82.38 45.8 126.8 60.5 99.46
Average of External Inguinal Ring Size (cm) 2.25 2.56 2.2 2.5 2.21 2.54
Average of Mesh Length (cm) 8.0 9.19 7.8 6.9 7.86 8.31
Average of Mesh Width (cm) 11.25 10.69 11.8 11.4 11.64 10.96
Average of Mesh Area (cm²) 87.0 98.63 97.8 81.9 94.71 92.19
Average of Length of Hernial Sac (cm) 4.75 7.25 7.0 8.2 6.36 7.62
Average of Width of Hernial Sac (cm) 3.25 4.06 4.7 4.55 4.29 4.25
Average of Height of Hernial Sac (cm) 2.5 3.18 2.88 3.5 2.75 3.32
Average of Volume of Hernial Sac (cm³) 46.5 113.28 135.4 134.8 110.0 121.56
Average of Operative Time (Minutes) 37.5 46.25 50.0 50.5 46.43 47.88

By comparing hernia metrics based on hernia site (Left = 0, Right = 1) across Group A (Normotensive) and Group B (Hypertensive), we found that:

  1. Hospitalization Duration: Similar across all groups, averaging ~5 days.
  2. Duration of Herniation: Right-sided hernias generally show longer durations than left-sided ones, especially in Group B.
  3. Hernia Dimensions: Right-sided hernias tend to have slightly larger lengths, widths, and volumes compared to left-sided ones in both groups.
  4. Hernial Sac Metrics: Right-sided hernias are associated with larger hernial sac dimensions and volumes, particularly in Group B.
  5. Operative Time: Higher for right-sided hernias, especially in Group B.

These data may indicate notable differences in metrics between right and left hernias, with right-sided hernias having longer duration of herniation, showing larger dimensions and longer operative times overall.

In attempt to understand if the type of inguinal hernia (Direct: Oblique) could influence the outcomes of hernioplasty, we conducted the following comparison (Table 13).

Table 13: Comparison of Hernia Characteristics, Surgical Parameters, and Hospitalization Data by Hernia Type (Direct/Oblique).

Metric Group A (Oblique) Group A (Direct) Group B (Oblique) Group B (Direct) Grand Total (Oblique) Grand Total (Direct)
Average Total Hospitalization (beds/day) 4.42 5.63 5.4 4.5 4.86 5.0
Average Duration of Herniation (Months) 26.92 21.5 28.5 16.9 27.64 18.94
Average Hernia Length (cm) 6.83 7.0 8.4 6.3 7.55 6.61
Average Hernia Width (cm) 4.46 5.0 4.8 4.6 4.61 4.78
Average Hernia Height (cm) 3.5 4.5 2.5 4.33 3.1 4.4
Average Hernia Volume (cm³) 84.17 87.13 70.7 101.9 78.05 95.33
Average External Inguinal Ring Size (cm) 2.46 2.56 2.4 2.3 2.43 2.42
Average Mesh Length (cm) 9.42 8.25 8.7 6.0 9.09 7.0
Average Mesh Width (cm) 10.42 11.38 12.2 11.0 11.23 11.17
Average Mesh Area (cm²) 96.25 96.38 113.7 66.0 104.18 79.5
Average Length of Hernial Sac (cm) 6.83 6.63 9.3 5.9 7.95 6.22
Average Width of Hernial Sac (cm) 3.25 4.88 4.9 4.35 4.0 4.58
Average Height of Hernial Sac (cm) 2.75 4.0 3.11 3.29 2.9 3.5
Average Volume of Hernial Sac (cm³) 64.63 152.88 179.8 90.4 116.98 118.17
Average Operative Time (Minutes) 42.92 46.88 57.0 43.5 49.32 45.0

By comparing between Oblique (Type = 0) and Direct (Type = 1) hernias across Groups A (Normotensive) and B (Hypertensive) we found:

  1. Hospitalization Duration: Similar across all groups, slightly longer for Direct hernias in Group A.
  2. Duration of Herniation: Oblique hernias generally had a longer duration than Direct ones, especially in Group B.
  3. Hernia Dimensions: Direct hernias exhibited larger widths and volumes overall, particularly in Group B.
  4. Mesh Characteristics: Oblique hernias required larger meshes (area and dimensions), especially in Group B.
  5. Hernial Sac Metrics: Oblique hernias tended to have larger lengths, whereas Direct hernias had higher volumes.
  6. Operative Time: Longer for Direct hernias in Group A but slightly shorter for Group B.

These data may indicate notable differences in metrics between oblique and direct inguinal hernias, where oblique inguinal hernias having longer duration of herniation, while direct inguinal hernias were found to attain larger volumes in hypertensive patients.

These findings could suggest differences in surgical and hernia metrics depending on inguinal hernia site and type.

Analyzing the correlation between type of anathesia and other metrics during open anterior inguinal hernia repair we found: [Table 14].

Table 14: Comparison of Metrics Based on Type of Anaesthesia (Spinal = 1, Endotracheal = 0)

Metric Group A (Endotracheal) Group A (Spinal) Group B (Spinal) Grand Total (Endotracheal) Grand Total (Spinal)
Average Total Hospitalization (beds/day) 5.00 4.89 4.95 5.00 4.92
Average Duration of Herniation (Months) 63.00 20.50 22.70 63.00 21.66
Average Hernia Length (cm) 10.50 6.50 7.35 10.50 6.95
Average Hernia Width (cm) 6.00 4.53 4.70 6.00 4.62
Average Hernia Height (cm) 3.50 3.83 3.29 3.50 3.54
Average Hernia Volume (cm³) 215.50 70.89 86.30 215.50 79.00
Average External Inguinal Ring Size (cm) 3.25 2.42 2.35 3.25 2.38
Average Mesh Length (cm) 13.50 8.44 7.35 13.50 7.87
Average Mesh Width (cm) 11.50 10.72 11.60 11.50 11.18
Average Mesh Area (cm²) 160.50 89.17 89.85 160.50 89.53
Average Length of Hernial Sac (cm) 9.00 6.50 7.60 9.00 7.08
Average Width of Hernial Sac (cm) 4.50 3.83 4.63 4.50 4.25
Average Height of Hernial Sac (cm) 3.00 3.00 3.19 3.00 3.10
Average Volume of Hernial Sac (cm³) 108.00 99.03 135.10 108.00 118.01
Average Operative Time (Minutes) 37.50 45.28 50.25 37.50 47.89

By comparing surgical and hernia metrics between Spinal and Endotracheal anesthesia, we found:

  1. Hospitalization Duration: Similar across groups, with Spinal anesthesia having slightly shorter durations.
  2. Duration of Herniation: Significantly longer for Endotracheal cases (63 months) compared to Spinal anesthesia (21.66 months).
  3. Hernia Dimensions: Larger hernia lengths and volumes were associated with Endotracheal anesthesia.
  4. Mesh Characteristics: Endotracheal cases required larger meshes compared to Spinal.
  5. Operative Time: Longer for Spinal anesthesia, averaging 47.89 minutes compared to 37.50 minutes for Endotracheal.

Our findings could suggest that Endotracheal anesthesia is linked with the cases of longer hernia durations and larger meshes, while Spinal anesthesia is more common for less severe cases with shorter operative times.

By comparing the duration of total hospitalization between both groups we estimated its correlation with arterial hypertension [Table 15].

Table 15: Comparison of Total Hospitalization Duration in both Groups.

Metric Group A (Normotensive) Group B (Hypertensive)
Mean 4.9 4.95
Variance 2.31 1.10
Observations 20 20
Pooled Variance 1.70 -
t Stat -0.12 -
P(T<=t) two-tail 0.90 -
t Critical two-tail 2.02 -

The p-value (0.90) indicates no statistically significant difference in hospitalization duration between the two groups.

Upon comparing the effect of duration of herniation upon the surgical outcomes in both groups [Table 16].

Table 16: Comparison of Duration of Herniation (Months) in both Groups

Metric Group A (Normotensive) Group B (Hypertensive)
Mean 24.75 22.7
Variance 1473.57 388.22
Observations 20 20
Pooled Variance 930.89 -
t Stat 0.21 -
P(T<=t) two-tail 0.83 -
t Critical two-tail 2.02 -

The p-value (0.83) suggests no statistically significant difference in the duration of herniation between the groups.

Upon comparing the average operative-times in both groups aiming at estimating possible effects of arterial hypertension on the time of hernia repair [Table 17].

Table 17: Comparison of Operative Time (Minutes) in Group A and Group B

Metric Group A (Normotensive) Group B (Hypertensive)
Mean 44.5 50.25
Variance 115.53 159.14
Observations 20 20
Pooled Variance 137.34 -
t Stat -1.55 -
P(T<=t) two-tail 0.13 -
t Critical two-tail 2.02 -

The p-value (0.13) indicates no statistically significant difference in operative time between the two groups.

CONCLUSION

In our study, we found that duration of herniation, operative-time, total hospitalization stays as well as the complications during both the postoperative and short-term follow up periods, for all these metrics—the results of the t-tests show no statistically significant differences between Group A (Normotensive Patients) and Group B (Hypertensive Patients), suggesting that arterial hypertension status does not significantly impact these metrics even with the presence of comorbidities.

On the other hand, right sided inguinal hernias, were shown to have larger dimensions and longer operative times in comparison to left sided inguinal hernias. Furthermore, direct inguinal hernias were found to attain larger volumes in hypertensive patients. These findings could suggest that the site and type of inguinal hernia could affect the outcomes of hernia repair, regarding size of mesh and operative-time.

CONFLICTS OF INTEREST

Authors have no conflict of interest to declare.

FUNDING

This publication was prepared without any external source of funding.

AUTHOR CONTRIBUTIONS

Andrey Protasov, Mekhaeel Mekhaeel, Sameh Salem, Khalid Al-Tekreeti - conceptualization, writing original draft, review and editing, project administration; Mekhaeel Mekhaeel, Sameh Salem, Khalid Al-Tekreeti, Eman Abdo, Abdalhakem alhatem– visualization, Andrey Protasov – supervision.

REFERENCES

  1. Protasov AV, Mekhaeel MSF, Salem SMA. The choice of the optimal mesh implant for hernioplasty operations depending on the properties of mesh implants. RUDN Journal of Medicine. 28;4:499-507. DOI: https://doi.org/10.22363/2313-0245-2024-28-4-499-507
  2. Mekhaeel MSF, Salem SMA, Protasov AV. Our experience in using self-gripping mesh during Liechtenstein repair. Randomized control trail. Journal of Surgery and Research. 2024;(7):533-536. DOI:10.26502/jsr.10020407
  3. Protasov AV, Mekhaeel MSF, Salem S. Outcomes of using both Self-gripping mesh and polypropylene meshes fixed by tacks in Liechtenstein repair. Russian journal of operative surgery and clinical anatomy. 2025 ;8((42)):5357. DOI: 10.17116/operhirurg2024804253
  4. Auger, N., Del Giorgio, F., Le-Nguyen, A., Bilodeau-Bertrand, M., & Piché, N. (2022). Maternal risk factors for paediatric inguinal hernia. British Journal of Surgery, 109(1), 129-135. DOI: 10.1093/bjs/znab337
  5. Henriksen, N. A., Yadete, D. H., Sorensen, L. T., Ågren, M. S., & Jorgensen, L. N. Connective tissue alteration in abdominal wall hernia. British Journal of Surgery, 2021;98(2), 210–219. DOI: 10.1002/bjs.7339
  6. Serra R, Bracale UM, Conforto R, Roncone A, Ielapi N, Michael A, Sodo M, Di Taranto MD, Mastroroberto P, Serraino GF, et al. Association between Inguinal Hernia and Arterial Disease: A Preliminary Report. Biology. 2021;10(8):736. DOI: 10.3390/biology10080736
  7. S. A. Antoniou, G. A. Antoniou, F. A. Granderath and C. Simopoulosm. The role of matrix metalloproteinases in the pathogenesis of abdominal wall hernias. European journal of clinical investigation. 2009; (39)11:953-959. DOI: 10.1111/j.1365-2362.2009.02199.x
  8. Ponticos M, Smith BD. Extracellular matrix synthesis in vascular disease: hypertension, and atherosclerosis. J Biomed Res. 2014;28(1):25-39. DOI: 10.7555/JBR.27.20130064
  9. Irene Hinterseher, Milena Miszczuk, Florian Corvinu, Carolin Zimmermann, Mariana Estrelinha, Diane T. Smelser, Helena Kuivaniemi. Do Hernias Contribute to Increased Severity of Aneurysmal Disease among Abdominal Aortic Aneurysm Patients? Aorta (Stamford) 2021; 09(01): 009-020. DOI: 10.1055/s-0040-1719113
  10. Lehnert, B., Wadouh, F. High coincidence of inguinal hernias and abdominal aortic aneurysms. Annals of Vascular Surgery. 1992;(6):134–137. DOI: 10.1007/BF02042733
  11. Kuo-Chuan Hung, Ying-Jen Chang, Cheuk-Kwan Sun, Jhi-Joung Wang, Yi-Chen Chen, Shih-Feng Weng, Chin-Chen Chu. Association of hernia with subsequent aortic aneurysm in geriatric patients. The Journal of Thoracic and Cardiovascular Surgery. 2021;(162)6:1668-1677.e2. DOI: 10.1016/j.jtcvs.2020.01.100
  12. Ramasamy, Akilesh. Python based simulation and treatment planning in Craniofacial Surgery: Advances and Challenges. 2019. DOI:10.13140/RG.2.2.21091.71203
  13. Taha, A., Enodien, B., Frey, D. M., & Taha-Mehlitz, S. The development of artificial intelligence in hernia surgery: a scoping review. Frontiers in Surgery. 2022; 9:908014. DOI: 10.3389/fsurg.2022.908014
  14. Vogel R and Mück B. Artificial Intelligence—What to Expect From Machine Learning and Deep Learning in Hernia Surgery. J. Abdom. Wall Surg. 2024;3:13059. DOI: 10.3389/jaws.2024.13059
  15. Huang, Estella Y; Chung, Daniel; Sandler, Bryan J; Jacobsen, Garth R; Horgan, Santiago; Broderick, Ryan C. The future of robotics in the treatment of abdominal wall hernias: A narrative review. International Journal of Abdominal Wall and Hernia Surgery.2023;6(2):81-91. DOI:10.4103/ijawhs.ijawhs_18_23


back

 



Europäische Wissenschaftliche Gesellschaft